Volumes Archive
Vol. 45, Number 3, 2003
Effect of Crataegus tanacetifolia Extract on Total Body Ion Concentration in Normal Rats
Crataegus tanacetifolia Ekstresinin Normal Sıçanlarda Vücut iyon Konsantrasyonuna Etkisi
Hüsniye Birman*, Nihal Salmayenli**, Gülay Melikoglu*** and Ali H. Meriçli***
*lstanbul University, Faculty of Medicine, Department of Physiology, Çapa Istanbul, Turkey
**Istanbul University, Faculty of Medicine, Department of Clinical Biochemistry, Çapa Istanbul, Turkey
***Istanbul University, Faculty of Pharmacy, Department of Pharmacognosy, Beyazıt, Istanbul,Turkey
Abstract
Since ancient times Cralaegus species have been used in traditional medicine all around the world, especially flavonoids, procyanidins, aromatic acids as well as amine type constituents were found to be responsible for itscardioactivity. In the present study we have investigated body. ion concentration of the rats giving aqueous leaf extract of C. tanacetifolia (50mg/kg), for thirty days via gavage.
We observed that the potassium, phosphat and calcium concentrations have increased significantly.This data suggest that ion changes may playa role in hypotensive activity.
Key words: Crataegus tanacetifolia; chronic use; body ion concentration; rat; potassium
