Volumes Archive
Vol. 45, Number 3, 2003
Spectrophotometric Method for the Determination of Paracetamol and Levodopa in Pharmaceutical Preparation
Eyad S.M. Abu-Nameh, Murad I.H.Helaleh and Ali AJ-Omai
Department of Basic Science, Faculty of Applied Science, AI-Balqa Applied University, Sa'alt, Jordan, Kuwait Institute for Scientific Research, Central Analytical Laboratory, P.O. Box 24885, Safat 13109, Kuwait.
Abstract
An indirect method for the determination of paracetamol and levodopa in described. The method based on the extraction of iodine. Beer's law obeyed over the concentration range 0.1-0.6 mg/mL and 0.1-0.2 mg/mL at 520 nm, with apparent molar absorptivity of 0.88xl 05 L/cmmol and 0.85x165 L/cmmol for paracetemol and levodopa, respectively. The precision and accuracy of the proposed method and the effect of various diverse ions have been studied and the analysis of pamcetamol and levodopa in pharmaceutical preparations have been carried out. The results obtained were compared with those of the reference method.
Key words: Extraction spectrophotometry, determination, paracetamol and levodopa, pharmaceutical preparation
